It plays a crucial role in cellular detoxification, immune function, and skin health
Primary Care Guidelines for B12 and Folate Testing Indications for B12 and Folate Testing No need to check B12 levels in patient on parenteral B12 treatment (they will always be high) There is no indication to check GPA or INF purely because of family history of autoimmune disease or hypothyroidism Care should be taken when prescribing folic acid alone If folic acid is given to a patient who is actually b12 deficient, this may precipitate irreversible neurological complications References 1
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10.1089/acm.2006.12.881 Summary Keywords vitamin B12, efficacy, bioavailability, therapeutic approaches, meta-analysis, cobalamin Citation Mazur M, Ndokaj A, Salerno C, Vallone J, Ardan R, Bietolini S, Carrouel F, Wilk A, Sarig R, Ottolenghi L and Bourgeois D (2025) Efficacy of sublingual and oral vitamin B12 versus intramuscular administration: insights from a systematic review and meta-analysis